Therapeutic Target Database

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A database to provide information about the known and explored therapeutic protein and nucleic acid targets, the targeted disease, pathway information and the corresponding drugs directed at each of these targets. Also included in this database are links to relevant databases containing information about target function, sequence, 3D structure, ligand binding properties, enzyme nomenclature and drug structure, therapeutic class, clinical development status. All information provided are fully referenced.
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Statistics of this database

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This database currently contains 1,894 targets, including 348 successful, 292 clinical trial and 1,254 research targets, and 5,028 drugs, including 1,514 approved, 1,212 clinical trial and 2,302 experimental drugs (3,382 small molecules and 649 antisense drugs with available strucuture or oligonucleotide sequence). Targets and drugs in this database cover 61 protein biochemical class and 140 drug therapeutic classes respectively.
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How to cite our database

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Chen X, Ji ZL, Chen YZ. TTD: Therapeutic Target Database. Nucleic Acids Res. 2002; 30(1):412-415. PubMed

Last update by

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October 18th, 2009
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